Acute Humanin Therapy Attenuates Myocardial Ischemia and Reperfusion Injury in Mice
نویسندگان
چکیده
منابع مشابه
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice.
OBJECTIVE Humanin (HN), an endogenous antiapoptotic peptide, has previously been shown to protect against Alzheimer's disease and a variety of cellular insults. We evaluated the effects of a potent analog of HN (HNG) in an in vivo murine model of myocardial ischemia and reperfusion. METHODS AND RESULTS Male C57BL6/J mice (8 to 10 week old) were subjected to 45 minutes of left coronary artery ...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2010
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.110.205997